This really depends on a number of factors. Considerations such as how many people will work in the space, whether multiple desks are required, what needs to be stored in the space, will there be large office equipment such as printers that will need to be accommodated in the room, will all affect the space needed.
Ultimately, the answer is that we will create a Home Office or Study Zone that is both comfortable and functional with sufficient storage within the space you have available.